Santiago de Compostela, 19-22 de Junio de 2018

1st Meeting in Translational Pharmacology

38th SEF national meeting/9th SEFF meeting

Book of Abstracts
Programme
Useful Information
www.sef2018.es

Premios y Menciones a las mejores comunicaciones concedidos en el 38th National Meeting Sociedad Española de Farmacología.

Premio a la Mejor Comunicación Libre Oral

• Is visfatin involved in the vascular dysfunction associated with diabesity and ageing? Mariella Ramos-Gonzalez, Susana Vallejo, San Hipólito-Luengo Alvaro, Romero Alejandra, Valencia Inés, Cercas Elena, Romacho T, Gómez Cerezo JF, Peiró Concepción, Sánchez-Ferrer CF. (Spain)
• Aporphine, 1-benzylisoquinoline and phenanthrene alkaloids as D2-dopaminergic ligands. Laura Vila, Laura Moreno, Andrea G. Silva, Marián Castro, María Isabel Loza, María Jesús Sanz, Diego Cortes, Nuria Cabedo. (Spain)
• Sodium-glucose cotransporter-2 inhibition reduces Angiotensin-II Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Knockout mice. Rebeca Ortega, Aida Collado, Francisca Selles, Jose T Real, María Jesús Sanz and Laura Piqueras (Spain)
• The probiotic Lactobacillus fermentum preventes dysbiosis and vascular oxidative stress in rats with hypertension induced by chronic nitric oxide blockade. Marta Toral, Iñaki Robles-Vera, Néstor de la Visitación, Manuel Sánchez, Miguel Romero, Mónica Olivares, Rosario Jiménez, Juan Duarte (Spain)
• ApoE-/- mice without CCR3 receptor present hastened atherosclerosis. Aida Collado, Elena Domingo, Laura Perez-Alos, Patrice Marques, Eva Perello, José T. Real, Laura Piqueras, Juan F. Ascaso, Maria-Jesus Sanz (Spain)

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Premio a la Mejor Comunicación Libre Póster

• Towards extracellular vesicle therapeutics: Annexin-A1 as a potential chondroprotective microvesicle effector in osteoarthritis. Miguel Tofiño-Vian, María José Vázquez, Isabel Guillén, María Dolores Pérez del Caz, Miguel Ángel Castejón, María José Alcaraz (Spain)
• SUCNR1 as a new pharmacological target for intestinal fibrosis. Jesús Cosín-Roger, Dolores Ortiz-Masia, Dulce Macias-Ceja, Laura Gisbert, Pedro Salvador, Sara Calatayud, Maria Dolores Barrachina
• Novel Imidazoline I2 Receptor Ligands for cognitive decline treatment. Mercè Pallàs, Christian Griñan-Ferre, Sònia Abás, Sergio Rodríguez-Arévalo, Andrea Bagán, Fotini Vasilopoulou, Luis F. Callado, Jesús A García-Sevilla, M. Julia García-Fuster, Belén Pérez, Carmen Escolano
• The spinal administration of the chemokine CCL4 can activate analgesic mechanisms in mice. Mario García-Domínguez, Ana Lastra, Agustín Hidalgo, Luis Menéndez, Ana Baamonde
• A Pharmacology practical class about the use of experimental animals and alternative methods. Matilde Sierra Vega, M. Nélida Fernández Martínez, Juan José García Vieitez, M. José Diez Liébana, Ana M. Sahagún Prieto, Raquel Díez Láiz, Juan Felipe García Sierra

Mención a la Mejor Comunicación Libre Oral

• Targeting metabolic and endothelial functions: the role of ALDH2. Ginevra Nannelli, Valentina Giorgio, Sandra Donnini, Paolo Bernardi, Marina Ziche
• Pain threshold evaluation after PF-3845, a FAAH inhibitor, administration in cafeteria-induced abstinence in rat: role of cannabinoid and opioid receptors. Roberto Russo, Carmen Avagliano, Claudia Cristiano, Carmen De Caro, Carlo Cifani, MV. Micioni Di Bonaventura, Maria Elena Giusepponi, Silvana Gaetani, Giuseppina Mattace Raso, Rosaria Meli, Antonio Calignano.
• ALDH1A1 is a novel regulator of tumor angiogenesis in breast cancer. Valerio Ciccone, Erika Terzuoli, Sandra Donnini, Lucia Morbidelli, Marina Ziche.
• ADRA2A gene expression and epigenetic regulation in postmortem prefrontal cortex of subjects with schizophrenia. G. Rivero, I.Brocos-Mosquera, J.J. Meana, L.F. Callado.
• Reinterpreting anomalous competitive binding experiments using G protein-coupled receptor homodimers: consequences of radioligand-competitor allosteric interactions. Verònica Casadó-Anguera, Estefanía Moreno, Josefa Mallol, Sergi Ferré, Enric I. Canela, Antoni Cortés and Vicent Casadó.

Mención a la Mejor Comunicación Libre Póster

• A superpotent bivalent ligand for dopamine D2 receptor homodimers. Verònica Casadó-Anguera, Daniel Pulido, Laura López, Estefania Moreno, Sergi Ferré, Arnau Cordomí, Antoni Cortés, Leonardo Pardo, Miriam Royo, Vicent Casadó.
• Evaluation of long-term desipramine administration on alpha2-adrenoceptors regulating noradrenaline and serotonin release in rat frontal cortex. Itziar Muneta-Arrate, Igor Horrillo, Blanca Perez-Palomar, Leyane Martinez-Alberdi, Jorge E. Ortega, J. Javier Meana.
• Serotonin-2A homodimers are needed for signalling via both phospholipase A2 and phospholipase C in transfected CHO cells. Alba Iglesias, Marta Cimadevila, María Isabel Cadavid, José Brea, María Isabel Loza.
• Cannabidiol, via sigma 1 receptors, alleviates NMDA-induced seizures and stroke damage. Elsa Cortés-Montero, Yara Onetti, María Rodríguez-Muñoz, Javier Garzón, Pilar Sánchez-Blazquez.
• Protective effects of probiotics and short-chain fatty acids consumption in spontaneously hypertensive rats. Miguel Romero, YIñaki Robles-Vera, Néstor de la Visitación, Marta Toral, Manuel Sánchez, Oscar Bañuelos, Rosario Jiménez, Juan Duarte.

Invited societies (by alphabetical order): French Pharmacological Society/Helenic Pharmacological Society/Italian Pharmacological Society/Portuguese Pharmacological Society
Drug discovery processes have experienced a dramatic change in the last years moving from in-house programs to the Open Innovation paradigm where public-private partnerships are being stablished looking for more efficient processes. Thus, there is a new place for pharmacology in the global Open Innovation framework playing a new key role to leap over the gap from basic transformational science to real therapeutic solutions.
Within this open innovation framework and focusing in the translation of pharmacological results the meeting will focus in Translational Pharmacology, being a joint meeting of the Spanish Pharmacological Society and the Spanish Pharmacogenomics and Pharmacogenetics Society
Furthermore the French, Helenic, Italian and Portuguese pharmacological societies are going to participate as invited societies allowing sharing the top-class research carried out by the members of these societies.
The program includes plenary lectures, roundtables and poster sessions for sharing and discussing the novel advances in our disciplines. We also want to offer a networking environment for young researchers, thus those communications selected by the scientific committee will be presented as short communications in the main roundtables. We look forward to seeing you in Santiago de Compostela in 2018.

Comisión Jóvenes Investigadores de la SEF. Actividades Congreso SEF 2018

La Comisión Jóvenes Investigadores de la SEF ha organizado las siguientes actividades a celebrar el 19 de junio en el 38º Congreso de la Sociedad (Santiago de Compostela) en la sesión que tendrá lugar de 15:00 a 17:00:

1. Ponencia «Communicating Science: Institutions, Communicating Sciences: Institutions, the Media and New Formats» por el Dr. Alberto Aparici (Universidad de Valencia)
2. «Your research in one minute». Se proyectarán vídeos resumen de investigación elaborados por jóvenes investigadores que deseen dar difusión de manera divulgativa a su tema de investigación.
3. «Meet the Pharmacologist», sesión de encuentro entre los jóvenes participantes con los ponentes sénior que participen en el Congreso

Se requiere inscripción para las actividades 2 y 3.
Se puede encontrar información sobre cómo participar en los siguientes enlaces:
«Your research in one minute»
«Meet the Pharmacologist»

Venue

The meeting will be held at Hotel Puerta del Camino in Santiago de Compostela from June 19th to June 22nd 2018