Neuroquímica y Neurodegeneración

Neuroquímica y Neurodegeneración

Datos de Contacto
Rafael Rodriguez Puertas
grupos de investigación

Neuroquímica y Neurodegeneración

Líneas de investigación

  • Development of new treatments based on neurolipids for neurodegenerative diseases. Dementia of the Alzheimer’s type
  • Development of new analytical methods for neuropharmacology.
  • Modulation of the GPCR activity by membrane lipid microenviromnment
  • LIPOTYPER. A new web-based software to anatomically quantify lipotypes in tissue slices.

Metodología in vitro

  • Radioligand binding; autoradiography; western blotting
  • Immunohistochemistry, Immunofluorescence, Elisa immunoassays
  • Imaging mass spectrometry; lipotyping in slices

Metodología in vivo

  • Rodent behavior tests for learning and memory
  • Rat brain organotypic cultures
  • Cell cultures of cells overexpressing GPCRs

Equipamiento

  • Core facility for imaging mass spectrometry
  • Radioisotope certified lab for beta radiation
  • Inverted fluorescence microscope for immunofluorescence studies of cell and organotypic cultures

Additional Information

  • Experience in collaboration with biotech and pharmaceutical companies fo drug discovery